Molecular Genetics

Christoph Englert (Group Leader)

Characterisation of 'disease genes' in the model organisms mouse and zebrafish, regulation of gene expression, biology of telomeres.

For more information look at the Molecular Genetics Group page of the Fritz Lipmann Institute (FLI).

Selected Publications

Hartmann N, Reichwald K, Wittig I, Dröse S, Schmeisser S, Lück C, Graf M, Gausmann U, Terzibasi E, Cellerino A, Ristow M, Brandt U, Platzer M, Englert C:
Mitochondrial DNA copy number and function decrease with age in the short-lived fish Nothobranchius furzeri.
Aging Cell. 2011; [Epub ahead of print]
Graf M, Cellerino A, Englert C:
Gender separation increases somatic growth in females but does not affect lifespan in Nothobranchius furzeri.
PLoS One. 2010; 5:e11958.
Bollig F, Perner B, Besenbeck B, Köthe S, Ebert C, Taudien S, Englert C:
A highly conserved retinoic acid responsive element controls wt1a expression in the zebrafish pronephros.
Development. 2009; 136:2883-92.
Hartmann N, Reichwald K, Lechel A, Graf M, Kirschner J, Dorn A, Terzibasi E, Wellner J, Platzer M, Rudolph KL, Cellerino A, Englert C:
Telomeres shorten while Tert expression increases during ageing of the short-lived fish Nothobranchius furzeri.
Mech Ageing Dev. 2009; 130:290-6.
Reichwald K, Lauber C, Nanda I, Kirschner J, Hartmann N, Schories S, Gausmann U, Taudien S, Schilhabel MB, Szafranski K, Glöckner G, Schmid M, Cellerino A, Schartl M, Englert C, Platzer M:
High tandem repeat content in the genome of the short-lived annual fish Nothobranchius furzeri: a new vertebrate model for aging research.
Genome Biol. 2009; 10:R16.