Molecular Biology

Leibniz Institute on Aging - Fritz Lipmann Institute (FLI)

Stephan Diekmann (Group Leader)

Peter Hemmerich

Structural and functional analysis of subnuclear complexes. Systems biology approaches for quantitative modelling of nuclear protein complex assembly in living cells.

For more information look at the group pages of Stephan Diekmann or Peter Hemmerich of the Fritz Lipmann Institute (FLI).

Selected Publications

• Marthandan S, Murphy MP, Billett E, Barnett Y:
  An investigation of the effects of MitoQ on human peripheral mononuclear cells.
  Free Radic Res. 2011; 45:351-8.
• Hemmerich P, Schmiedeberg L, Diekmann S:
  Dynamic as well as stable protein interactions contribute to genome function and maintenance.
  Chromosome Res. 2011; 19:131-151.
• Lenser T, Weisshart K, Ulbricht T, Klement K, Hemmerich P:
  Fluorescence fluctuation microscopy to reveal 3D architecture and function in the cell nucleus.
  Methods Cell Biol. 2010; 98:2-33.
• Lang M, Jegou T, Chung I, Richter K, Münch S, Udvarhelyi A, Cremer C, Hemmerich P, Engelhardt J, Hell SW, Rippe K:
  Three-dimensional organization of promyelocytic leukemia nuclear bodies.
  J Cell Sci. 2010; 123:392-400.
• Larbi A, Cabreiro F, Zelba H, Marthandan S, Combet E, Friguet B, Petropoulos I, Barnett Y, Pawelec G:
  Reduced oxygen tension results in reduced human T cell proliferation and increased intracellular oxidative damage and susceptibility to apoptosis upon activation.
  Free Radic Biol Med. 2010; 48:26-34.